A long time source of reliable stem cells has been from the bone marrow. The CD34 hematopoietic stem cells have been used in bone marrow transplants for many years and are now a staple treatment for many blood derived cancers. There are other subpopulations of stem cells in the BM which have growing interest in research. Although these cells are rare, they may be potent enough to repair certain tissue types.

Mesenchymal stem cells (MSC) were first isolated and characterized from the bone marrow. Since then, MSCs have been identified in other tissue types. PrimeGen has interest in working on these cell types and developing procedures to translate them into a clinical setting.